Guerilla Strike is the second mission in Warriors of World War III, the player takes the role of a Kilo 1 operative; Mark Fisher.

The mission takes place in the jungles of Cuba where an American B-52 bomber carrying a nuclear weapon crash landed, Kilo one was sent in to find and secure the weapon before the cuban military could find it, after sneaking pass guerilla forces, Kilo 1 arrives at the crash site to find an army of guerilla forces, a gunfight erupts between the two factions until Kilo 1 achieves victory, however the nuclear is not at the site, just as all hope seems lost, informatio comes through the Kilo 1 that the weapon was taken and put on a cargo ship heading to Brazil.